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Shipping Information
Distributed: DNA (dried). Rehydrate with TE. (amount: 2 ug)
Comments
Restriction digests of the clone give the following sizes (kb): BamHI--3.7, 0.64; EcoRI--3.0, 1.35; HindIII--4.4; PstI--3.3, 0.5, 0.27; XbaI--4.4.
The insert contains the following restriction sites (nt from the 5' EcoRI site): XmnI--72, AccI--142, BglII--159, PstI--318; BamHI--634; NarI--916; SmaI--1060.
This clone encodes the synthesis of a 50 kDa fusion protein recognized by anti-NADPH oxidase antisera.
Detects a mRNA of 1.4 kb.
References
Volpp BD, et al. Cloning of the cDNA and functional expression of the 47-kilodalton cytosolic component of human neutrophil respiratory burst oxidase. Proc. Natl. Acad. Sci. USA 86: 7195-7199, 1989. PubMed: 2550933
Volpp BD, et al. Two cytosolic neutrophil oxidase components absent in autosomal chronic granulomatous disease. Science 242: 1295-1297, 1988. PubMed: 2848318
. Medical sciences: correction. Proc. Natl. Acad. Sci. USA 86: 9563, 1989.
Casimir CM, et al. Autosomal recessive chronic granulomatous disease caused by deletion at a dinucleotide repeat. Proc. Natl. Acad. Sci. USA 88: 2753-2757, 1991. PubMed: 2011585
